Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 6/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314988 | 0.88 | CAPN1 (0.53) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7320994 | 0.87 | PPARA (0.53) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7323388 | 0.87 | CAPN1 (0.57) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7320502 | 0.85 | CTSL (0.52) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7318494 | 0.84 | CTSK (0.54) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7314067 | 0.84 | CTSL (0.45) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7314076 | 0.84 | CTSL (0.45) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7323822 | 0.83 | CTSL (0.48) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7319742 | 0.83 | TACR1 (0.62) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7326797 | 0.79 | TACR1 (0.56) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-B1 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD (CH) | 1994-03-16 | — | — | EP | disclosed |
| US-5158936-A | Treating or prevention of tissue damage, inflammation, bone resporpption and muscular dystrophy | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| US-5055451-A | Prevent tissue damage | SYNTEX INC. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |