Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | FABP4 | P15090 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311048 | 0.79 | FBP1 (0.44) | CYP3A4FBP1 | |
| SCHEMBL7310790 | 0.77 | CA1 (0.38) | CA1CA2HDAC1 | |
| SCHEMBL1589651 | 0.71 | GPR17 (0.46) | FABP4HDAC1GPR17FBP1 | |
| SCHEMBL7319801 | 0.70 | CYP3A4 (0.34) | CYP3A4 | |
| SCHEMBL7315192 | 0.70 | S1PR4 (0.39) | CA1CA2HDAC1 | |
| SCHEMBL8780587 | 0.69 | CNR1 (0.50) | HDAC1 | |
| SCHEMBL23831996 | 0.69 | CYP3A4 (0.37) | CA1CA2CYP3A4 | |
| SCHEMBL7317232 | 0.69 | CA1 (0.38) | CA1CA2HDAC1GPR17 | |
| SCHEMBL7308299 | 0.69 | CTSK (0.41) | HDAC1CYP3A4 | |
| SCHEMBL17594492 | 0.68 | HIF1A (0.47) | CA1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31617-E | ANTICOAGULANTS; HYPOTENSIVE AND BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-3932407-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTICOAGULANTS | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |