Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.67 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.67 |
| ▸ | CPB1 | P15086 | 1/20 | 0.63 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322295 | 1.00 | SIRT2 (0.67) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL7324738 | 0.89 | SIRT2 (0.67) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL9516479 | 0.87 | SIRT2 (0.62) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL28291230 | 0.87 | SIRT2 (0.86) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL19851643 | 0.87 | SIRT2 (0.86) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL30891387 | 0.86 | SIRT2 (0.75) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| Monoethanolamine SCHEMBL9496843 | 0.86 | ITGB3 (0.62) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL7388911 | 0.85 | SIRT2 (0.68) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL7322118 | 0.85 | SIRT2 (0.62) | SIRT2SIRT1SIRT3CPB1CPB2 | |
| SCHEMBL7322113 | 0.85 | SIRT2 (0.62) | SIRT2SIRT1SIRT3CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527764-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | claimed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | claimed |
| EP-0527764-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |