Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 13/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313141 | 0.88 | PDE3B (0.37) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7317849 | 0.88 | PDE3B (0.35) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7306654 | 0.87 | PDE3B (0.34) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7316963 | 0.87 | NPC1 (0.36) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7316772 | 0.87 | PDE3B (0.34) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7312004 | 0.82 | PDE4A (0.40) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7320125 | 0.82 | PDE4A (0.43) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL10670419 | 0.79 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7316952 | 0.76 | PDE3B (0.34) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7318642 | 0.76 | MAPT (0.34) | PDE3BPDE3ANPC1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761416-A | ENZYME INHIBITORS, INOTROPIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-02 | — | — | US | disclosed |
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |