⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11445607 | 0.98 | GAA (0.41) | — | |
| SCHEMBL7316858 | 0.82 | GAA (0.42) | — | |
| SCHEMBL7323862 | 0.79 | GAA (0.45) | — | |
| SCHEMBL9359144 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL9354852 | 0.76 | GAA (0.40) | — | |
| SCHEMBL15334778 | 0.75 | — | — | |
| SCHEMBL28171951 | 0.74 | — | — | |
| SCHEMBL9025311 | 0.73 | HCAR2 (0.50) | — | |
| SCHEMBL7217929 | 0.73 | — | — | |
| SCHEMBL25436967 | 0.71 | GAA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190202811-A1 | AMINOACYLINDAZOLE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES | THE ROCKEFELLER UNIVERSITY (US) | 2019-07-04 | — | — | US | disclosed |
| EP-1107956-A2 | USE OF 5-AMINO-PYRAZOL-DERIVATIVES FOR COMBATING MICRO-ORGANISMS | BAYER AG (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000011951-A2 | USE OF 5-AMINO-PYRAZOL-DERIVATIVES FOR COMBATING MICRO-ORGANISMS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-09 | — | — | WO | disclosed |
| EP-0802907-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AG (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021653-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |