Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7298416 | 0.99 | LTA4H (0.41) | LTA4HSLC18A3OPRM1KDM4EOPRD1 | |
| SCHEMBL707641 | 0.81 | KMT2A (0.42) | SLC18A3OPRM1OPRD1OPRK1 | |
| SCHEMBL7296841 | 0.81 | KMT2A (0.42) | SLC18A3OPRM1OPRD1OPRK1 | |
| SCHEMBL1525667 | 0.81 | KMT2A (0.42) | SLC18A3OPRM1OPRD1OPRK1 | |
| SCHEMBL706372 | 0.81 | KMT2A (0.38) | LTA4HOPRM1OPRD1OPRK1 | |
| SCHEMBL7293732 | 0.80 | SLC6A2 (0.40) | LTA4HOPRM1OPRD1OPRK1 | |
| SCHEMBL7293742 | 0.80 | SLC6A2 (0.40) | LTA4HOPRM1OPRD1OPRK1 | |
| SCHEMBL7293726 | 0.80 | SLC6A2 (0.40) | LTA4HOPRM1OPRD1OPRK1 | |
| SCHEMBL8236994 | 0.79 | HTR7 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13566531 | 0.78 | KDM4E (0.41) | OPRM1KDM4EOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309043-A2 | Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-03-29 | — | — | EP | disclosed |