Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73202 | 1.00 | MCHR1 (0.43) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL74213 | 0.90 | MCHR1 (0.45) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL74214 | 0.90 | MCHR1 (0.45) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL83172 | 0.89 | MCHR1 (0.44) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL1463315 | 0.88 | MCHR1 (0.42) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL1463274 | 0.88 | MCHR1 (0.42) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL9884603 | 0.88 | MCHR1 (0.42) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL75693 | 0.87 | MCHR1 (0.44) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL75694 | 0.87 | MCHR1 (0.44) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 | |
| SCHEMBL9884601 | 0.87 | MCHR1 (0.41) | MCHR1SMN1; SMN2PROKR1EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| EP-1763302-B1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042938-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042938-A1 | Chemical Compounds | CHRM1, MRM1, H1-0 | MCHR1 439/4885SMN1; SMN2 1351/4885PROKR1 2813/4885 |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | ACHE, CHRM1, CHRM2 | MCHR1 391/4885SMN1; SMN2 1134/4885PROKR1 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.