Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555243 | 0.83 | POLB (0.46) | POLBSYKNTSR1L3MBTL1CTSL | |
| SCHEMBL19456479 | 0.81 | POLB (0.47) | POLBSYKNTSR1L3MBTL1 | |
| SCHEMBL7331832 | 0.77 | CTSS (0.43) | POLBSYKNTSR1L3MBTL1CTSS | |
| SCHEMBL7323132 | 0.77 | PPARA (0.46) | POLBSYKL3MBTL1CTSSLTA4H | |
| SCHEMBL23491247 | 0.75 | SYK (0.45) | POLBSYKNTSR1L3MBTL1MAPT | |
| SCHEMBL23491355 | 0.75 | SYK (0.45) | POLBSYKNTSR1L3MBTL1MAPT | |
| SCHEMBL9555246 | 0.75 | POLB (0.53) | POLBSYKNTSR1L3MBTL1MAPT | |
| SCHEMBL2499502 | 0.73 | POLB (0.47) | POLBSYKL3MBTL1MAPT | |
| SCHEMBL30878162 | 0.73 | POLB (0.47) | POLBSYKL3MBTL1MAPT | |
| SCHEMBL30307663 | 0.73 | POLB (0.47) | POLBSYKL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |