Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456479 | 0.88 | POLB (0.47) | POLBSYKNTSR1L3MBTL1 | |
| SCHEMBL7320388 | 0.83 | POLB (0.43) | POLBSYKNTSR1L3MBTL1CTSL | |
| SCHEMBL23491247 | 0.82 | SYK (0.45) | POLBSYKNTSR1L3MBTL1 | |
| SCHEMBL23491355 | 0.82 | SYK (0.45) | POLBSYKNTSR1L3MBTL1 | |
| SCHEMBL30307663 | 0.80 | POLB (0.47) | POLBSYKL3MBTL1 | |
| SCHEMBL30878162 | 0.80 | POLB (0.47) | POLBSYKL3MBTL1 | |
| SCHEMBL2499502 | 0.80 | POLB (0.47) | POLBSYKL3MBTL1 | |
| SCHEMBL4679985 | 0.78 | SYK (0.47) | POLBSYKL3MBTL1CTSK | |
| SCHEMBL9555345 | 0.77 | CTSK (0.46) | CTSLCTSBCTSSCTSK | |
| SCHEMBL16284728 | 0.75 | SYK (0.50) | POLBSYKL3MBTL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236899-A | Enhanced sensitivity to antitumor agents | MERCK & CO., INC. (US) | 1993-08-17 | — | — | US | disclosed |
| US-4914188-A | ANTIBODY INHIBITORS | MERCK & CO., INC. (US) | 1990-04-03 | — | — | US | disclosed |