Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308560 | 0.88 | GAA (0.32) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL7318247 | 0.76 | PDE3B (0.35) | ALDH1A1MAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL7320413 | 0.75 | SMN1; SMN2 (0.39) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7311384 | 0.74 | PDE3B (0.40) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7311387 | 0.71 | PDE3B (0.40) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7320425 | 0.71 | PDE3B (0.37) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL7311837 | 0.69 | PDE3B (0.48) | — | |
| SCHEMBL7317263 | 0.69 | PDE3B (0.50) | — | |
| SCHEMBL7319280 | 0.69 | CASP6 (0.35) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL10374700 | 0.67 | SMN1; SMN2 (0.35) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |