Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320408 | 0.88 | ALDH1A1 (0.33) | GAACASP6HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7319790 | 0.77 | PDE3B (0.35) | CASP6ALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL7308565 | 0.76 | SMN1; SMN2 (0.37) | GAACASP6ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7312890 | 0.72 | CASP6 (0.37) | GAACASP6ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7321041 | 0.70 | CASP6 (0.35) | GAACASP6ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7311837 | 0.69 | PDE3B (0.48) | — | |
| SCHEMBL7317263 | 0.68 | PDE3B (0.50) | — | |
| SCHEMBL7316670 | 0.68 | PDE3B (0.41) | HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7320520 | 0.66 | PDE3B (0.47) | HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7318247 | 0.66 | PDE3B (0.35) | CASP6ALDH1A1SMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |