Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304959 | 0.91 | ACHE (0.58) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL2603247 | 0.89 | ACHE (0.68) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL8539143 | 0.86 | ACHE (0.60) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL9785724 | 0.86 | ACHE (0.64) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9785687 | 0.84 | ACHE (0.62) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL9785683 | 0.83 | ACHE (0.60) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL7288362 | 0.83 | ACHE (0.60) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL12261876 | 0.83 | ACHE (0.59) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL20233114 | 0.83 | ACHE (0.59) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL25945885 | 0.83 | ACHE (0.59) | ACHEALDH1A1EPHX1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610192-A1 | ETHER DERIVATIVES OF ALKYL PIPERIDINES AND PYRROLIDINES AS ANTIPSYCHOTIC AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-08-17 | — | — | EP | disclosed |
| US-5317024-A | Administering to mammals | DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-05-31 | — | — | US | disclosed |
| US-5252586-A | Ether derivatives of alkyl piperidines and pyrrolidines as antipsychotic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| WO-1993009094-A1 | ETHER DERIVATIVES OF ALKYL PIPERIDINES AND PYRROLIDINES AS ANTIPSYCHOTIC AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |