SCHEMBL9304959

SCHEMBL9304959

C[C@@H](O)[C@@H]1CCN(C(=O)c2ccccc2)C1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.58
ALDH1A1 P00352 2/20 0.56
KMT2A Q03164 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
EPHX1 P07099 1/20 0.50
KDM4E B2RXH2 1/20 0.50
L3MBTL3 Q96JM7 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
BLM P54132 1/20 0.49
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
ATM Q13315 1/20 0.48
MGLL Q99685 1/20 0.47
HPGD P15428 1/20 0.47
POLB P06746 1/20 0.47
SLC18A3 Q16572 1/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7320518 0.91 ACHE (0.66) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL25945885 0.89 ACHE (0.59) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL20233114 0.89 ACHE (0.59) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL12261876 0.89 ACHE (0.59) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL2603247 0.83 ACHE (0.68) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL24486549 0.82 ACHE (0.55) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL20927003 0.82 ACHE (0.51) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL10099560 0.81 HPGD (0.54) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL12261870 0.81 HPGD (0.54) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1
SCHEMBL9785724 0.80 ACHE (0.64) ACHEALDH1A1KMT2ASMN1; SMN2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6072999-A None JP disclosed
JP-H0672999-A PRODUCTION OF AMINOALKYLPYRROLIDINE COMPOUND FUJISAWA PHARMACEUT CO LTD 1994-03-15 JP disclosed