Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604021 | 0.92 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL9675581 | 0.75 | — | — | |
| SCHEMBL28599420 | 0.74 | NAAA (0.34) | ALDH1A1TSHRHPGDHIF1A | |
| SCHEMBL11218965 | 0.72 | TSHR (0.46) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL2254844 | 0.72 | — | — | |
| SCHEMBL15854876 | 0.70 | — | — | |
| SCHEMBL7785077 | 0.70 | — | — | |
| SCHEMBL7785079 | 0.70 | — | — | |
| SCHEMBL322669 | 0.69 | — | — | |
| Butadiene SCHEMBL3329726 | 0.69 | ALDH1A1 (0.54) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389711-B2 | Pharmaceutical composition for treatment of cancer and asthma | KUREHA CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-8138159-B2 | Composition for inhibiting function of human Flt3 | TAKARA BIO INC. (JP) | 2012-03-20 | — | — | US | disclosed |
| EP-2377934-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER AND ASTHMA | Kureha Corporation (JP) | 2011-10-19 | — | — | EP | disclosed |
| US-20110245325-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER AND ASTHMA | KUREHA CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20110105582-A1 | Composition for inhibiting function of human flt3 | TAKARA BIO INC. (JP) | 2011-05-05 | — | — | US | disclosed |