SCHEMBL7320712

SCHEMBL7320712

O=C(CC1Cc2ccccc2C1)N1C=CSC=C1C(=O)N1CCC[C@H]1CO

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PREP P48147 15/20 0.45
CHRM2 P08172 2/20 0.40
CHRM4 P08173 2/20 0.40
CHRM1 P11229 2/20 0.40
CHRM3 P20309 2/20 0.40
SPHK2 Q9NRA0 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7324249 0.87 PREP (0.46) PREP
SCHEMBL7331463 0.83 F2 (0.40) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL7323425 0.83 PREP (0.47) PREP
SCHEMBL7354544 0.82 PREP (0.51) PREP
SCHEMBL8161141 0.79 PREP (0.63) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL8161224 0.79 PREP (0.63) PREPCHRM2CHRM4CHRM1CHRM3
SCHEMBL7327641 0.79 PREP (0.42) PREP
SCHEMBL7349204 0.78 PREP (0.55) PREP
SCHEMBL7324397 0.76 PREP (0.47) PREP
SCHEMBL9791373 0.76 PREP (0.46) PREPCHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed