Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 18/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327641 | 0.92 | PREP (0.42) | PREP | |
| SCHEMBL7325498 | 0.87 | PREP (0.42) | PREPHTR1ASIGMAR1 | |
| SCHEMBL7327936 | 0.85 | GBA1 (0.41) | PREPHTR1ASIGMAR1 | |
| SCHEMBL7329968 | 0.81 | PREP (0.46) | PREP | |
| SCHEMBL7325825 | 0.80 | P2RX7 (0.40) | PREPPTGDR2 | |
| SCHEMBL7350647 | 0.78 | PREP (0.39) | PREPPTGDR2 | |
| SCHEMBL7354544 | 0.77 | PREP (0.51) | PREP | |
| SCHEMBL7324249 | 0.77 | PREP (0.46) | PREP | |
| SCHEMBL7352189 | 0.76 | PREP (0.38) | PREP | |
| SCHEMBL7322434 | 0.76 | PREP (0.48) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |