SCHEMBL7349204

SCHEMBL7349204

O=C(C1=CSC=CN1C(=O)CC1Cc2ccccc2C1)N1CCSC1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PREP P48147 15/20 0.55
DPP4 P27487 4/20 0.38
DPP7 Q9UHL4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7354544 0.88 PREP (0.51) PREP
SCHEMBL7359386 0.87 PREP (0.45) PREPDPP4DPP7
SCHEMBL7327641 0.82 PREP (0.42) PREP
SCHEMBL7323490 0.81 PREP (0.46) PREPDPP4
SCHEMBL7354558 0.79 PREP (0.41) PREPDPP4DPP7
SCHEMBL7324249 0.78 PREP (0.46) PREP
SCHEMBL7350647 0.78 PREP (0.39) PREP
SCHEMBL7320712 0.78 PREP (0.45) PREP
SCHEMBL7326813 0.77 PREP (0.37) PREPDPP4DPP7
SCHEMBL7352189 0.76 PREP (0.38) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017929-A Cholinesterase activator ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-01-25 US disclosed
EP-0754454-A1 CHOLINESTERASE ACTIVATOR ZERIA PHARMACEUTICAL CO., LTD. (JP) 1997-01-22 EP disclosed
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed