Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132717 | 0.89 | RARB (0.58) | PTPN11TP53MAPTRARBCA12 | |
| SCHEMBL7326102 | 0.88 | RARB (0.56) | PTPN11TP53MAPTRARBCA12 | |
| Trifluoroacetic Acid SCHEMBL7319226 | 0.86 | MAPT (0.42) | PTPN11TP53MAPTSMN1; SMN2RARB | |
| SCHEMBL6132844 | 0.82 | CA12 (0.53) | PTPN11TP53MAPTSMN1; SMN2RARB | |
| SCHEMBL6539767 | 0.79 | MAPT (0.57) | TP53MAPTRARBCA12CA1 | |
| SCHEMBL6539568 | 0.78 | TP53 (0.76) | TP53MAPTSMN1; SMN2RARBCA12 | |
| SCHEMBL10611011 | 0.77 | RARB (0.74) | PTPN11TP53RARBRXRARXRB | |
| SCHEMBL6135027 | 0.77 | TP53 (0.41) | TP53MAPTSMN1; SMN2RARBCA12 | |
| Trifluoroacetic Acid SCHEMBL7323575 | 0.76 | CA12 (0.46) | TP53MAPTSMN1; SMN2RARBCA12 | |
| Trifluoroacetic Acid SCHEMBL6538606 | 0.76 | TP53 (0.47) | TP53MAPTSMN1; SMN2RARBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |