Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PRKX | P51817 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327654 | 0.82 | CHRM1 (0.39) | CHRM1ROCK2PRKXPRKCEPRKCD | |
| SCHEMBL7326975 | 0.79 | CHRM1 (0.40) | CHRM1ROCK2PRKXPRKCEPRKCD | |
| SCHEMBL7360629 | 0.76 | CHRM1 (0.38) | CHRM1 | |
| SCHEMBL7328987 | 0.75 | COMT (0.35) | — | |
| SCHEMBL7320742 | 0.70 | CHRM1 (0.42) | CHRM1ROCK2PRKXPRKCEPRKCD | |
| SCHEMBL7324785 | 0.69 | ROCK2 (0.30) | ROCK2PRKXPRKCEPRKCDROCK1 | |
| SCHEMBL7327000 | 0.69 | CDK2 (0.31) | ROCK2PRKXPRKCEPRKCDROCK1 | |
| SCHEMBL7325026 | 0.69 | MAPT (0.33) | ROCK2ROCK1 | |
| SCHEMBL7326979 | 0.68 | CHRM1 (0.43) | CHRM1ROCK2PRKXPRKCEPRKCD | |
| SCHEMBL7327070 | 0.67 | ROCK2 (0.49) | ROCK2PRKCEPRKCDROCK1PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287696-B1 | ISOQUINOLINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0287696-A1 | Isoquinoline derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-10-26 | — | — | EP | disclosed |