Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787817 | 0.84 | AKR1C3 (0.53) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7787806 | 0.83 | AKR1C3 (0.52) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7790027 | 0.80 | AKR1C3 (0.51) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7790030 | 0.80 | AKR1C3 (0.51) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7782228 | 0.79 | AKR1C3 (0.50) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7782230 | 0.79 | AKR1C3 (0.50) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7320733 | 0.76 | DRD3 (0.61) | HTR7DRD3 | |
| SCHEMBL7791333 | 0.76 | AKR1C3 (0.54) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7791335 | 0.76 | AKR1C3 (0.54) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7786983 | 0.76 | AKR1C3 (0.48) | AKR1C3LMNAALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612378-A | TREATING THROMBOSIS, ISCHEMIA, STROKE, RESTENOSIS OR INFLAMMATION | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996039380-A1 | BIS-ARYLSULFONYLAMINOBENZAMIDE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1996-12-12 | — | — | WO | disclosed |