Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.61 |
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316591 | 0.88 | AKR1C3 (0.58) | — | |
| SCHEMBL7323404 | 0.88 | AKR1C3 (0.58) | — | |
| SCHEMBL8366229 | 0.84 | AKR1C3 (0.53) | — | |
| SCHEMBL8364333 | 0.84 | AKR1C3 (0.53) | — | |
| SCHEMBL9235211 | 0.83 | HTR7 (0.58) | DRD3DRD2HTR7POLB | |
| SCHEMBL8366252 | 0.83 | AKR1C3 (0.52) | — | |
| SCHEMBL10724572 | 0.80 | DRD3 (0.78) | DRD3DRD2ADRA1ASLC6A4SLC6A2 | |
| SCHEMBL7322835 | 0.79 | MEN1 (0.58) | POLB | |
| SCHEMBL27702845 | 0.78 | KDM1A (0.65) | POLB | |
| SCHEMBL7320774 | 0.76 | AKR1C3 (0.51) | DRD3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612378-A | TREATING THROMBOSIS, ISCHEMIA, STROKE, RESTENOSIS OR INFLAMMATION | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-03-18 | — | — | US | disclosed |