Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092622 | 0.91 | ALDH1A1 (0.55) | SLC9A1KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL11775657 | 0.84 | ALDH1A1 (0.49) | SLC9A1KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL11777699 | 0.84 | ALDH1A1 (0.49) | SLC9A1KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL8974037 | 0.83 | ALDH1A1 (0.47) | SLC9A1KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL11779113 | 0.83 | KCNH2 (0.49) | SLC9A1KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL10092616 | 0.83 | ALDH1A1 (0.47) | SLC9A1KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL7352221 | 0.82 | SLC9A1 (0.58) | SLC9A1KCNH2ALDH1A1LMNAHPGD | |
| SCHEMBL13167113 | 0.81 | NQO2 (0.49) | SLC9A1ALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL11777874 | 0.80 | NQO2 (0.56) | SLC9A1ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL11779695 | 0.79 | ALDH1A1 (0.44) | SLC9A1KCNH2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3946049-A | 5-PHENYL-2-FURAMIDOXIMES | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-23 | — | — | US | claimed |
| US-4882354-A | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0321431-A1 | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-06-21 | — | — | EP | disclosed |
| US-3946049-A | 5-PHENYL-2-FURAMIDOXIMES | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-23 | — | — | US | disclosed |