Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.66 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309896 | 0.85 | BIRC2 (0.70) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7320279 | 0.84 | BIRC2 (0.76) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7320818 | 0.84 | BIRC2 (0.69) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7321243 | 0.80 | BIRC2 (0.69) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL11123333 | 0.79 | BIRC2 (0.74) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL9755830 | 0.76 | BIRC2 (0.70) | BIRC2MME | |
| SCHEMBL10949321 | 0.76 | BIRC2 (0.65) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL15223599 | 0.75 | ALDH1A1 (0.69) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL7313729 | 0.75 | BIRC2 (0.62) | BIRC2MMECYP2C9 | |
| SCHEMBL7321252 | 0.75 | BIRC2 (0.62) | BIRC2MMECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |