SCHEMBL732091

SCHEMBL732091

COC(=O)C(C)Oc1ccc(Oc2ccc(Br)cc2Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
TSHR P16473 2/20 0.45
NPSR1 Q6W5P4 2/20 0.43
FFAR1 O14842 1/20 0.43
HPGD P15428 1/20 0.42
KDM4E B2RXH2 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PNLIP P16233 2/20 0.40
ALDH2 P05091 1/20 0.40
AAK1 Q2M2I8 1/20 0.39
ACACB O00763 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10963427 0.88 KMT2A (0.49) MAPTMEN1KMT2AL3MBTL1TSHR
Diclofop-Methyl SCHEMBL1495949 0.87 MAPT (0.56) MAPTMEN1KMT2AL3MBTL1TSHR
Diclofop-Methyl SCHEMBL29446684 0.87 MAPT (0.56) MAPTMEN1KMT2AL3MBTL1TSHR
SCHEMBL10662568 0.87 FFAR1 (0.47) MEN1KMT2ATSHRNPSR1FFAR1
SCHEMBL9420195 0.87 FFAR1 (0.47) MEN1KMT2ATSHRNPSR1FFAR1
Diclofop-Methyl SCHEMBL9139752 0.87 MAPT (0.56) MAPTMEN1KMT2AL3MBTL1TSHR
Diclofop-Methyl SCHEMBL55275 0.87 MAPT (0.56) MAPTMEN1KMT2AL3MBTL1TSHR
SCHEMBL10848257 0.87 TSHR (0.47) MAPTMEN1KMT2AL3MBTL1TSHR
SCHEMBL11141407 0.86 TSHR (0.45) MAPTMEN1KMT2AL3MBTL1TSHR
SCHEMBL10965425 0.85 L3MBTL1 (0.47) MAPTMEN1KMT2AL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330904-B1 Herbicidal agent in the form of aqueous microemulsions HOECHST AG (DE) 1994-04-20 EP claimed
US-4973352-A Herbicidal agents in the form of aqueous transparent microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-27 US claimed
US-4414020-A AMIDOXIMES AS SAFENING AGENTS HOECHST AG (DE) 1983-11-08 US claimed
US-4370489-A POSTEMERGENCE, PREEMERGENCE HERBICIOES; WEED GRASSES HOECHST AKTIENGESELLSCHAFT (DE) 1983-01-25 US claimed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 US disclosed
EP-1893016-B1 WATER-IN-OIL SUSPOEMULSIONS BAYER IP GMBH (DE) 2017-09-13 EP disclosed
EP-1651039-B1 OIL SUSPENSION CONCENTRATE CONTAINING DIFLUFENICAN BAYER IP GMBH (DE) 2017-01-04 EP disclosed
EP-1928232-B1 SOLID FORMULATION BAYER IP GMBH (DE) 2016-07-13 EP disclosed
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2015-09-03 US disclosed
EP-2908639-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES Bayer Cropscience AG (DE) 2015-08-26 EP disclosed
US-9102623-B2 Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use BAYER CROPSCIENCE AG (DE) 2015-08-11 US disclosed
EP-2144879-B1 PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION BAYER IP GMBH (DE) 2015-04-08 EP disclosed
US-4564382-A HERBICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-14 US disclosed
EP-0154153-A1 Use of aryloxy compounds as antidotes HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-11 EP disclosed
US-4531969-A Combatting growth of weeds HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-30 US disclosed
US-4414020-A AMIDOXIMES AS SAFENING AGENTS HOECHST AG (DE) 1983-11-08 US disclosed
US-4370489-A POSTEMERGENCE, PREEMERGENCE HERBICIOES; WEED GRASSES HOECHST AKTIENGESELLSCHAFT (DE) 1983-01-25 US disclosed
EP-0002800-B1 Optically active alpha-phenoxypropionic acid dervatives HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-02 EP disclosed
EP-0031938-A2 Use of aryloxy(thio)carboxylic acid nitriles and amidoximes as antidotes against herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-15 EP disclosed
US-4252980-A Process for the manufacture of (phenoxy or benzyl)-phenoxypropionic acid methyl esters HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150245610-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES AADAC, PFAS, CBR3 MAPT 4268/4885MEN1 4245/4885KMT2A 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.