Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202133 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL8799524 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HSD11B1MAPTLMNAPKM | |
| SCHEMBL7319765 | 0.71 | ALDH1A1 (0.49) | ALDH1A1HSD11B1MAPTLMNAPKM | |
| SCHEMBL4216728 | 0.71 | SMN1; SMN2 (0.55) | ALDH1A1MAPTLMNACACNA1BAPBA1 | |
| SCHEMBL8879926 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL5742037 | 0.70 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL25669620 | 0.69 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNACACNA1BAPBA1 | |
| SCHEMBL4209751 | 0.69 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL5742034 | 0.69 | SMN1; SMN2 (0.48) | ALDH1A1MAPTLMNACACNA1BAPBA1 | |
| SCHEMBL4204057 | 0.69 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNACACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019707-A2 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |