Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | POLB | P06746 | 4/20 | 0.76 |
| ▸ | GLS | O94925 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323305 | 0.94 | ALDH1A1 (0.72) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL14975757 | 0.89 | ALDH1A1 (0.95) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL15709879 | 0.87 | ALDH1A1 (1.00) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL14986945 | 0.87 | ALDH1A1 (1.00) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL2395874 | 0.85 | — | — | |
| SCHEMBL14977428 | 0.84 | ALDH1A1 (0.86) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL17402474 | 0.81 | ALDH1A1 (0.79) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL10952704 | 0.79 | ALDH1A1 (0.76) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL11412602 | 0.79 | ALDH1A1 (0.96) | ALDH1A1POLBGLSL3MBTL1GAA | |
| SCHEMBL1968819 | 0.78 | ALDH1A1 (0.88) | ALDH1A1POLBGLSL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592453-B1 | AMINOALKYL-SUBSTITUTED 2-AMINO-1,3,4-THIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 1998-12-16 | — | — | EP | disclosed |
| US-5424312-A | Treating central nervous system disorders, high blood pressure | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0592453-A1 | AMINOALKYL-SUBSTITUTED 2-AMINO-1,3,4-THIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992022541-A1 | AMINOALKYL-SUBSTITUTED 2-AMINO-1,3,4-THIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | WO | disclosed |