Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.42 |
| ▸ | MMP9 | P14780 | 11/20 | 0.42 |
| ▸ | MMP13 | P45452 | 11/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.42 |
| ▸ | NAMPT | P43490 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316861 | 0.93 | MMP9 (0.43) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7321111 | 0.89 | MMP1 (0.43) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7313293 | 0.87 | MMP1 (0.43) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7311825 | 0.85 | MMP9 (0.48) | MMP1MMP9MMP13ADAM17NAMPT | |
| Hydrochloric Acid SCHEMBL7319142 | 0.82 | MMP9 (0.51) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7312077 | 0.82 | MMP9 (0.43) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7317369 | 0.81 | MMP9 (0.43) | MMP1MMP9MMP13ADAM17NAMPT | |
| Hydrochloric Acid SCHEMBL7323801 | 0.79 | MMP9 (0.48) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7316225 | 0.79 | NAMPT (0.47) | MMP1MMP9MMP13ADAM17NAMPT | |
| Hydrochloric Acid SCHEMBL7323698 | 0.78 | MMP9 (0.52) | MMP1MMP9MMP13ADAM17NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |