Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.80 |
| ▸ | PKM | P14618 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.80 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323716 | 0.89 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL29627864 | 0.89 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL11191379 | 0.83 | CHRM1 (0.71) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL501316 | 0.82 | CHRM1 (0.69) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL4710824 | 0.76 | CHRM1 (0.64) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL4708893 | 0.76 | CHRM1 (0.60) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL2843067 | 0.75 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7331808 | 0.75 | CHRM1 (0.71) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL10741591 | 0.75 | CHRM1 (0.71) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7323866 | 0.75 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902794-A | Triazolo-benzodiazepines | THE UPJOHN COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-3992408-A | CHEMICAL INTERMEDIATES | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3987052-A | SEDATIVES, TRANQUILIZERS, MUSCLE RELAXANTS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |