Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7323046 | 0.99 | NPC1 (0.47) | RAB9ANPC1FDFT1CHRNB2CHRNA7 | |
| Hydrochloric Acid SCHEMBL7323334 | 0.93 | NPC1 (0.47) | RAB9ANPC1FDFT1LTA4HMAOB | |
| SCHEMBL7324506 | 0.89 | LTA4H (0.49) | LTA4HHRH3 | |
| SCHEMBL3221856 | 0.88 | CHRNB4 (0.46) | CHRNA7CHRNA4CHRNB4CHRNA3SLC6A2 | |
| SCHEMBL3221853 | 0.88 | CHRNB4 (0.46) | CHRNA7CHRNA4CHRNB4CHRNA3SLC6A2 | |
| SCHEMBL3221893 | 0.88 | CHRNB4 (0.46) | CHRNA7CHRNA4CHRNB4CHRNA3SLC6A2 | |
| Hydrochloric Acid SCHEMBL7329408 | 0.88 | LTA4H (0.48) | LTA4H | |
| SCHEMBL7329701 | 0.86 | LTA4H (0.50) | RAB9ANPC1FDFT1CHRNB2CHRNA7 | |
| SCHEMBL7328652 | 0.86 | LTA4H (0.46) | CHRNA7CHRNA4CHRNB4CHRNA3LTA4H | |
| Hydrochloric Acid SCHEMBL7320238 | 0.85 | LTA4H (0.49) | RAB9ANPC1FDFT1CHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625979-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| WO-1993015073-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |