Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7322738 | 0.99 | LTA4H (0.45) | LTA4HHRH3CHRNB4CHRNA3DRD2 | |
| SCHEMBL3221893 | 0.94 | CHRNB4 (0.46) | CHRNB4CHRNA3DRD2EGFRPOLB | |
| SCHEMBL3221853 | 0.94 | CHRNB4 (0.46) | CHRNB4CHRNA3DRD2EGFRPOLB | |
| SCHEMBL3221856 | 0.94 | CHRNB4 (0.46) | CHRNB4CHRNA3DRD2EGFRPOLB | |
| SCHEMBL7321121 | 0.86 | LTA4H (0.48) | LTA4HHRH3CHRNB4CHRNA3DRD2 | |
| SCHEMBL7322367 | 0.86 | RAB9A (0.48) | LTA4HHRH3CHRNB4CHRNA3MAPT | |
| SCHEMBL7324506 | 0.86 | LTA4H (0.49) | LTA4HHRH3 | |
| SCHEMBL7323953 | 0.85 | HRH3 (0.48) | LTA4HHRH3 | |
| Hydrochloric Acid SCHEMBL7329408 | 0.85 | LTA4H (0.48) | LTA4H | |
| Hydrochloric Acid SCHEMBL7330696 | 0.85 | LTA4H (0.47) | LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625979-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| WO-1993015073-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |