Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322379 | 1.00 | FKBP1A (0.54) | FKBP1AMEN1KMT2ANPSR1HPGD | |
| Hydrochloric Acid SCHEMBL7278911 | 0.88 | MAPT (0.54) | MEN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL7269161 | 0.86 | FKBP1A (0.62) | FKBP1AKMT2AHPGDSMN1; SMN2POLB | |
| SCHEMBL9832234 | 0.86 | FKBP1A (0.62) | FKBP1AKMT2AHPGDSMN1; SMN2POLB | |
| SCHEMBL7269160 | 0.86 | FKBP1A (0.62) | FKBP1AKMT2AHPGDSMN1; SMN2POLB | |
| SCHEMBL7269018 | 0.81 | MEN1 (0.56) | FKBP1AMEN1KMT2ANPSR1HPGD | |
| SCHEMBL7269464 | 0.78 | FKBP1A (0.58) | FKBP1AMEN1KMT2ANPSR1HPGD | |
| SCHEMBL7269457 | 0.78 | FKBP1A (0.58) | FKBP1AMEN1KMT2ANPSR1HPGD | |
| SCHEMBL7291450 | 0.78 | FKBP1A (0.58) | FKBP1AMEN1KMT2ANPSR1HPGD | |
| SCHEMBL19390153 | 0.76 | MEN1 (0.61) | FKBP1AMEN1KMT2ANPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| US-5364844-A | Hypotensive agents | SANKYO COMPANY, LIMITED (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0326364-B1 | Renin inhibitory oligopeptides, their preparation and use | SANKYO CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0326364-A2 | Renin inhibitory oligopeptides, their preparation and use | Sankyo Company Limited (JP) | 1989-08-02 | — | — | EP | disclosed |