Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322584 | 1.00 | ACE (0.55) | ACEMMESRCTPSAB1TPSD1 | |
| SCHEMBL7330368 | 0.97 | ACE (0.55) | ACEMMESRCTPSAB1TPSD1 | |
| SCHEMBL7330364 | 0.97 | ACE (0.55) | ACEMMESRCTPSAB1TPSD1 | |
| SCHEMBL7391741 | 0.87 | ACE (0.48) | ACEMMESRCTPSAB1TPSD1 | |
| SCHEMBL7422816 | 0.86 | SRC (0.49) | ACESRC | |
| SCHEMBL7426897 | 0.86 | ACE (0.41) | ACESRC | |
| SCHEMBL7333844 | 0.85 | ACE (0.49) | ACEMMESRCTPSAB1TPSD1 | |
| SCHEMBL7333849 | 0.85 | ACE (0.49) | ACEMMESRCTPSAB1TPSD1 | |
| SCHEMBL7325000 | 0.85 | ACE (0.58) | ACEMMESRCTPSAB1TPSD1 | |
| SCHEMBL7324992 | 0.85 | ACE (0.58) | ACEMMESRCTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598071-A | ANGIOTENSIN INHIBITORS/ | E. R. SQUIBB & SONS, INC. (US) | 1986-07-01 | — | — | US | disclosed |
| US-4567167-A | INHIBITOR OF ANGIOTENDIN CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4533661-A | Certain 3-phosphinyl-amino-2-oxo-1H-azepine-1-acetic acid derivatives having anti-hypertensive activity | E. R. SQUIBB & SONS, INC. (US) | 1985-08-06 | — | — | US | disclosed |