Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.49 |
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330364 | 0.86 | ACE (0.55) | SRCACE | |
| SCHEMBL7330368 | 0.86 | ACE (0.55) | SRCACE | |
| SCHEMBL7426897 | 0.86 | ACE (0.41) | SRCACE | |
| SCHEMBL7322584 | 0.86 | ACE (0.55) | SRCACE | |
| SCHEMBL7322575 | 0.86 | ACE (0.55) | SRCACE | |
| SCHEMBL7423479 | 0.85 | SRC (0.53) | SRCACECASP1CASP8 | |
| SCHEMBL11104772 | 0.80 | LMNA (0.38) | ACE | |
| SCHEMBL11104778 | 0.80 | LMNA (0.38) | ACE | |
| SCHEMBL7433313 | 0.79 | ACE (0.58) | ACE | |
| SCHEMBL7433309 | 0.77 | ACE (0.36) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |
| US-4460579-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1984-07-17 | — | — | US | disclosed |