Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327185 | 0.93 | CARM1 (0.68) | BCHECARM1PRMT6TMEM97SIGMAR1 | |
| Oxalic Acid SCHEMBL7316888 | 0.89 | BCHE (0.66) | BCHECARM1PRMT6CHRM3TMEM97 | |
| Oxalic Acid SCHEMBL7327098 | 0.83 | SSTR5 (0.51) | CHRM3HRH3 | |
| Oxalic Acid SCHEMBL9368372 | 0.80 | CCR5 (0.48) | — | |
| Oxalic Acid SCHEMBL9368757 | 0.78 | SLC6A2 (0.45) | BCHE | |
| SCHEMBL4026157 | 0.77 | BCHE (1.00) | BCHE | |
| Oxalic Acid SCHEMBL9528351 | 0.77 | CHRNB4 (0.47) | — | |
| SCHEMBL4025061 | 0.76 | BCHE (0.64) | BCHECARM1PRMT6CHRM3TMEM97 | |
| SCHEMBL4013732 | 0.76 | CARM1 (0.54) | BCHECARM1PRMT6 | |
| SCHEMBL4023008 | 0.76 | BCHE (1.00) | BCHECARM1PRMT6TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |