Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321415 | 0.93 | HRH3 (0.54) | KMT2AMEN1HRH3SLC6A5 | |
| Oxalic Acid SCHEMBL7318747 | 0.88 | KMT2A (0.69) | KMT2AMEN1HRH3 | |
| Oxalic Acid SCHEMBL7320673 | 0.84 | KDM4E (0.61) | KMT2AMEN1HRH3 | |
| SCHEMBL7317633 | 0.83 | HRH3 (0.61) | KMT2AMEN1HRH3 | |
| Hydrochloric Acid SCHEMBL7322070 | 0.82 | HRH3 (0.60) | KMT2AMEN1HRH3 | |
| SCHEMBL7317615 | 0.82 | ALDH1A1 (0.59) | KMT2AMEN1HRH3 | |
| SCHEMBL7322566 | 0.81 | TMEM97 (0.61) | HRH3 | |
| Hydrochloric Acid SCHEMBL7316066 | 0.81 | HRH3 (0.50) | HRH3 | |
| Oxalic Acid SCHEMBL7318217 | 0.81 | SLC6A2 (0.53) | KMT2AMEN1HRH3 | |
| Hydrochloric Acid SCHEMBL9528327 | 0.81 | USP2 (0.58) | KMT2AMEN1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |