Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7322070 | 0.99 | HRH3 (0.60) | HRH3MEN1KMT2AMAOBKDM4E | |
| SCHEMBL7321415 | 0.89 | HRH3 (0.54) | HRH3MEN1KMT2AMAOB | |
| SCHEMBL7324710 | 0.87 | HRH3 (0.51) | HRH3MAOBKDM4E | |
| SCHEMBL7321964 | 0.86 | HRH3 (0.64) | HRH3 | |
| Hydrochloric Acid SCHEMBL9532080 | 0.86 | MAPK1 (0.52) | HRH3MAOBKDM4E | |
| SCHEMBL7317615 | 0.86 | ALDH1A1 (0.59) | HRH3MEN1KMT2A | |
| SCHEMBL7322566 | 0.86 | TMEM97 (0.61) | HRH3 | |
| SCHEMBL24429268 | 0.85 | HRH3 (0.53) | HRH3MEN1KMT2AMAOB | |
| Hydrochloric Acid SCHEMBL27431543 | 0.85 | SIGMAR1 (0.64) | HRH3 | |
| Hydrochloric Acid SCHEMBL9528327 | 0.85 | USP2 (0.58) | HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |