Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322906 | 1.00 | FKBP1A (0.52) | FKBP1AALDH1A1CYP3A4TSHRACE | |
| SCHEMBL28051124 | 0.86 | CMA1 (0.57) | CMA1CAPN1RENCTSKCTSL | |
| SCHEMBL1992452 | 0.85 | FKBP1A (0.60) | FKBP1AALDH1A1CYP3A4TSHRCMA1 | |
| SCHEMBL7320486 | 0.84 | SMN1; SMN2 (0.48) | ACEREN | |
| SCHEMBL7320499 | 0.84 | SMN1; SMN2 (0.48) | ACEREN | |
| SCHEMBL13413313 | 0.83 | FKBP1A (0.51) | FKBP1AACERENCTSKCTSL | |
| SCHEMBL28349215 | 0.82 | FKBP1A (0.56) | FKBP1AACERENCTSKCTSL | |
| SCHEMBL13413249 | 0.82 | FKBP1A (0.58) | FKBP1AACERENCTSKCTSL | |
| SCHEMBL13413216 | 0.82 | FKBP1A (0.53) | FKBP1AACERENCTSKCTSL | |
| SCHEMBL30051146 | 0.81 | ALDH1A1 (0.62) | FKBP1AALDH1A1CYP3A4TSHRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4691007-A | HUMAN LEUKOCYTE ELASTASE INHIBITORS | ICI AMERICAS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| US-4596789-A | Pharmaceuticals | ICI AMERICAS INC. (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0124317-A2 | Proline derivatives | ICI AMERICAS INC. (US) | 1984-11-07 | — | — | EP | disclosed |