Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326854 | 0.88 | MME (0.44) | MME | |
| SCHEMBL8249923 | 0.86 | MME (0.59) | MMEMMP3 | |
| SCHEMBL5870219 | 0.86 | MME (0.59) | MMEMMP3 | |
| SCHEMBL11206129 | 0.84 | MME (0.63) | MMEMMP3MMP2MMP12MMP13 | |
| SCHEMBL9617696 | 0.83 | LTA4H (0.55) | MME | |
| SCHEMBL9617697 | 0.83 | LTA4H (0.55) | MME | |
| SCHEMBL11011952 | 0.83 | MME (0.53) | MMEMMP3MMP2MMP1MMP12 | |
| SCHEMBL27691470 | 0.83 | LTA4H (0.55) | MME | |
| SCHEMBL9830052 | 0.82 | PSMB5 (0.49) | MMECTSL | |
| SCHEMBL9830035 | 0.82 | PSMB5 (0.49) | MMECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472380-A | CARBOXYALKYL DIPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4374829-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |