Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | YAP1 | P46937 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304614 | 0.90 | GPR119 (0.68) | GPR119FAAHYAP1ALDH1A1 | |
| SCHEMBL1923068 | 0.87 | GPR119 (0.67) | GPR119FAAHYAP1ALDH1A1 | |
| SCHEMBL7279217 | 0.84 | GPR119 (0.60) | GPR119FAAHYAP1 | |
| SCHEMBL7315022 | 0.83 | GPR119 (0.64) | GPR119FAAHYAP1 | |
| SCHEMBL7308698 | 0.82 | GPR119 (0.63) | GPR119FAAHITGB3ITGA2BYAP1 | |
| SCHEMBL7318758 | 0.82 | GPR119 (0.74) | GPR119FAAH | |
| SCHEMBL7280692 | 0.82 | GPR119 (0.62) | GPR119FAAHITGB3ITGA2BYAP1 | |
| SCHEMBL7312363 | 0.82 | GPR119 (0.62) | GPR119ITGB3ITGA2BYAP1 | |
| SCHEMBL4155287 | 0.81 | ALDH1A1 (0.59) | GPR119FAAHALDH1A1 | |
| SCHEMBL22032269 | 0.80 | GPR119 (0.52) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016697-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-02 | — | — | WO | claimed |
| WO-1993016697-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-02 | — | — | WO | disclosed |
| US-5227490-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1993-07-13 | — | — | US | disclosed |