Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315812 | 0.95 | CTRB1 (0.67) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL7322957 | 0.93 | CTRB1 (0.62) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL24224270 | 0.88 | CTRB1 (0.66) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL8395473 | 0.86 | CTRB1 (0.73) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL8248799 | 0.86 | CTRB1 (0.73) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL8247594 | 0.86 | CTRB1 (0.73) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL29599350 | 0.85 | CTRB1 (0.62) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL9243277 | 0.85 | CTRB1 (0.69) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL9243269 | 0.85 | CTRB1 (0.69) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL31084237 | 0.85 | CTRB1 (0.69) | CTRB1NPSR1KMT2ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-B1 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD (CH) | 1994-03-16 | — | — | EP | disclosed |
| US-5158936-A | Treating or prevention of tissue damage, inflammation, bone resporpption and muscular dystrophy | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| US-5055451-A | Prevent tissue damage | SYNTEX INC. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |