Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494452 | 0.89 | CYP1A2 (0.41) | CYP1A2CYP2C19KMT2AKDM4EPKM | |
| SCHEMBL8053728 | 0.88 | CYP1A2 (0.47) | CYP1A2CYP2C19KMT2AKDM4EPKM | |
| SCHEMBL17445904 | 0.87 | PDK2 (0.46) | CYP1A2CYP2C19KMT2AKDM4EPKM | |
| SCHEMBL2763056 | 0.84 | PDK2 (0.44) | CYP1A2CYP2C19KMT2APDK2LMNA | |
| SCHEMBL11205330 | 0.84 | SIGMAR1 (0.45) | CYP1A2CYP2C19KMT2AKDM4EPKM | |
| SCHEMBL3267624 | 0.83 | KDM4E (0.47) | KMT2AKDM4EPKMPDK2LMNA | |
| SCHEMBL15691586 | 0.83 | PDK2 (0.50) | CYP1A2CYP2C19KMT2AKDM4EPKM | |
| Dimethylamine SCHEMBL11470686 | 0.82 | CYP1A2 (0.44) | CYP1A2CYP2C19KMT2AKDM4EPKM | |
| SCHEMBL28886995 | 0.80 | KDM4E (0.41) | CYP1A2CYP2C19KMT2AKDM4EPKM | |
| SCHEMBL28045123 | 0.80 | PDK2 (0.52) | KDM4EPDK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |
| US-6106999-A | SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS | MITSUI CHEMICALS (JP) | 2000-08-22 | — | — | US | disclosed |
| WO-1999041227-A1 | TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-08-19 | — | — | WO | disclosed |