Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528730 | 0.86 | PDK2 (0.41) | KDM4EPKMLMNAOPRM1OPRD1 | |
| SCHEMBL7322958 | 0.83 | CYP1A2 (0.45) | KDM4EPKMLMNAKMT2APDK2 | |
| SCHEMBL250063 | 0.79 | GAA (0.54) | KDM4EPKMLMNAMMP2MMP9 | |
| SCHEMBL11494452 | 0.77 | CYP1A2 (0.41) | KDM4EPKMLMNAALDH1A1MAPT | |
| SCHEMBL11883145 | 0.77 | GAA (0.39) | KDM4EPKMLMNAOPRM1OPRD1 | |
| SCHEMBL17445904 | 0.77 | PDK2 (0.46) | KDM4EPKMLMNAALDH1A1KMT2A | |
| SCHEMBL11205330 | 0.76 | SIGMAR1 (0.45) | KDM4EPKMALDH1A1KMT2APDK2 | |
| SCHEMBL11884940 | 0.76 | KDM4E (0.34) | KDM4EPKMLMNAOPRM1OPRD1 | |
| SCHEMBL27531044 | 0.76 | MMP2 (0.39) | KDM4EPKMMMP2MMP9MMP3 | |
| SCHEMBL10490984 | 0.76 | ELANE (0.46) | LMNAALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645552-B1 | Electroluminescent devices made with double-spiro organic compounds | LG CHEMICAL LTD (KR) | 2010-05-05 | — | — | EP | disclosed |
| EP-1645552-A1 | Double-spiro organic compounds and electroluminescent devices | LG Chem, Ltd. (KR) | 2006-04-12 | — | — | EP | disclosed |
| US-6998487-B2 | Double-spiro organic compounds and organic electroluminescent devices using the same | LG CHEM, LTD. (KR) | 2006-02-14 | — | — | US | disclosed |
| US-6984462-B2 | Organic electroluminescent devices using double-spiro organic compounds | LG CHEM, LTD. (KR) | 2006-01-10 | — | — | US | disclosed |
| US-20040170863-A1 | Organic electroluminescent devices using double-spiro organic compounds | LG CHEM, LTD. (KR) | 2004-09-02 | — | — | US | disclosed |
| US-20040023060-A1 | Double-spiro organic compounds and organic electroluminescent devices using the same | LG CHEM, LTD. (KR) | 2004-02-05 | — | — | US | disclosed |
| EP-1294823-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG Chem, Ltd. (KR) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002088274-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG CHEM, LTD. (KR) | 2002-11-07 | — | — | WO | disclosed |