Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22260777 | 0.94 | KMT2A (0.55) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL6856717 | 0.89 | KMT2A (0.76) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL10761788 | 0.86 | HPGD (0.64) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL6096092 | 0.86 | KMT2A (0.63) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL9249394 | 0.86 | KMT2A (0.63) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL4001162 | 0.84 | KMT2A (0.66) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL10260429 | 0.84 | KMT2A (0.66) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL1544858 | 0.84 | KMT2A (0.62) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL29842346 | 0.84 | KMT2A (0.66) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL470710 | 0.84 | KMT2A (0.66) | KMT2AMAOBMEN1TSHRPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | claimed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | claimed |