Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001162 | 0.92 | KMT2A (0.66) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL6856717 | 0.90 | KMT2A (0.76) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL30622549 | 0.87 | TSHR (0.71) | TSHRPRSS1MAPK1POLBMAPT | |
| SCHEMBL617974 | 0.87 | TSHR (0.71) | TSHRPRSS1MAPK1POLBMAPT | |
| SCHEMBL6096092 | 0.87 | KMT2A (0.63) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL10761788 | 0.87 | HPGD (0.64) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL470710 | 0.86 | KMT2A (0.66) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL7322978 | 0.86 | KMT2A (0.62) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL17329448 | 0.86 | KMT2A (0.58) | KMT2AMAOBMEN1TSHRPRSS1 | |
| SCHEMBL7228185 | 0.86 | KMT2A (0.62) | KMT2AMAOBMEN1TSHRPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239243-A1 | Method of identifying compounds useful to treat neuronal degenerative diseases | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2009-09-24 | — | — | US | disclosed |
| US-20090017062-A1 | Methods and compounds to alter virus infection | IOWA RESEARCH FOUNDATION IOWA CENTERS FOR ENTERPRI (US) | 2009-01-15 | — | — | US | disclosed |
| US-20080261201-A1 | Methods and compounds to alter virus infection | UNIVERSITY OF IOWA RESEARCH FOUNDATION IOWA CENTERS FOR ENTERPRISE (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080206792-A1 | Method of identifying compounds useful to treat neuronal degenerative diseases | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-08-28 | — | — | US | disclosed |
| WO-1995022323-A1 | METHODS FOR CONTROLLING FREE RADICAL GENERATION BY INFLAMMATORY CELLS | IDUN PHARMACEUTICALS (US) | 1995-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017062-A1 | Methods and compounds to alter virus infection | CYBB, NOX4, NOX5 | KMT2A 1957/4885MAOB 329/4885MEN1 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.