Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754489 | 0.80 | MAPT (0.36) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL9762507 | 0.80 | MAPT (0.39) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL29105506 | 0.80 | MAPT (0.36) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL8953652 | 0.79 | MAPT (0.45) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL10487044 | 0.77 | MAPT (0.47) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL8342993 | 0.77 | ALDH1A1 (0.44) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL11405760 | 0.77 | MAPT (0.44) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL29105510 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL11077687 | 0.77 | ALDH1A1 (0.34) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL29105514 | 0.77 | GFER (0.35) | MAPTALDH1A1GAAMDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813553-A | Selective deuterated N-methylation method of polyazaaromatic compound | 四川大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-105829433-A | CROSSLINKABLE NITRILE RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT | 日本瑞翁株式会社 | 2016-08-03 | — | — | CN | disclosed |
| CN-1035824-A | The preparation method of 1-alkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-27 | — | — | CN | disclosed |
| US-4716170-A | 5-[1H-(5-membered-N-aromatic heteryl)-1-yl]-1,6-naphthyridin-2(1H)-ones and their cardiotonic use | STERLING DRUG INC. (US) | 1987-12-29 | — | — | US | disclosed |
| US-4697021-A | 1,6-dihydro-6-oxo-3-pyridinecarbonitriles, intermediates for cardiotonic agents | STERLING DRUG INC. (US) | 1987-09-29 | — | — | US | disclosed |
| US-4678799-A | PARASITICIDES | MERCK & CO., INC. (US) | 1987-07-07 | — | — | US | disclosed |
| US-4657915-A | INOTROPIC AGENTS | STERLING DRUG INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4634772-A | 2-[2-(di-lower-alkylamino)-1-propenyl]-6-methoxy-3-pyridinecarbonitriles, intermediates for cardiotonic agents | STERLING DRUG INC. (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0189853-A2 | 1,6-Naphthyridin-2(1H)-ones having cardiotonic activity and preparation | STERLING DRUG INC. (US) | 1986-08-06 | — | — | EP | disclosed |
| EP-0166533-A1 | Quinolone inotropic agents | Pfizer Limited (GB) | 1986-01-02 | — | — | EP | disclosed |
| US-4021442-A | Production of 1-alkyl-5-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |