Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323015 | 0.80 | MAPT (0.46) | MAPTALDH1A1L3MBTL1GAAMDM2 | |
| SCHEMBL29105506 | 0.75 | MAPT (0.36) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL11754489 | 0.75 | MAPT (0.36) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL1716189 | 0.75 | TYMS (0.44) | MAPTALDH1A1TDP1PKMNPSR1 | |
| SCHEMBL29105514 | 0.72 | GFER (0.35) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL11077687 | 0.72 | ALDH1A1 (0.34) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL29105510 | 0.72 | ALDH1A1 (0.41) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL8965133 | 0.72 | ALDH1A1 (0.34) | MAPTALDH1A1GAAMDM2SMN1; SMN2 | |
| SCHEMBL5182827 | 0.71 | MAPT (0.40) | MAPTALDH1A1PKMGAAMDM2 | |
| SCHEMBL11347718 | 0.71 | ALDH1A1 (0.37) | MAPTALDH1A1GAAMDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |