Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321045 | 0.88 | ITGB3 (0.44) | ITGB3ITGA2BPOLBKDM1ACA2 | |
| SCHEMBL7321784 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BCA2 | |
| SCHEMBL7331527 | 0.84 | ITGB3 (0.54) | ITGB3TSHRITGB1ITGAVITGA5 | |
| SCHEMBL7350185 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BPOLBMAPTCA2 | |
| SCHEMBL7323153 | 0.82 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL8906500 | 0.82 | CA1 (0.46) | ITGB3ITGA2BPOLBCA2 | |
| SCHEMBL8906494 | 0.82 | CA1 (0.46) | ITGB3ITGA2BPOLBCA2 | |
| SCHEMBL8895885 | 0.82 | TSHR (0.46) | POLBKDM1ATSHRHDAC1HDAC2 | |
| SCHEMBL7354349 | 0.80 | ITGB3 (0.67) | ITGB3ITGA2B | |
| SCHEMBL7352608 | 0.78 | ITGB3 (0.52) | ITGB3ITGA2BPOLBTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550159-A | Peptide mimics useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5453440-A | Amidine functional group on benzene ring, anticoagulants | G. D. SEARLE & CO. (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1993018058-A1 | PEPTIDES MIMICS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-09-16 | — | — | WO | disclosed |