Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344701 | 0.89 | MAPT (0.44) | TSHRMAPTHTTLTA4HRAB9A | |
| SCHEMBL8906494 | 0.83 | CA1 (0.46) | POLB | |
| SCHEMBL8906500 | 0.83 | CA1 (0.46) | POLB | |
| SCHEMBL7321784 | 0.82 | ITGB3 (0.48) | — | |
| SCHEMBL7323167 | 0.82 | ITGB3 (0.56) | TSHRMAPTHTTPOLBHDAC1 | |
| SCHEMBL6978278 | 0.81 | KMT2A (0.47) | MAPTHTTPOLBKMT2A | |
| SCHEMBL7423126 | 0.80 | POLB (0.45) | MAPTHTTLTA4HPOLBMEN1 | |
| SCHEMBL7862257 | 0.79 | KMT2A (0.41) | MAPTHTTRAB9APOLBMEN1 | |
| SCHEMBL7354349 | 0.78 | ITGB3 (0.67) | — | |
| SCHEMBL7321045 | 0.76 | ITGB3 (0.44) | LTA4HRAB9APOLBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614360-B1 | SUBSTITUTED BETA-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1997-03-19 | — | — | EP | disclosed |