Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.50 |
| ▸ | MMP9 | P14780 | 9/20 | 0.50 |
| ▸ | MMP1 | P03956 | 9/20 | 0.50 |
| ▸ | NAMPT | P43490 | 6/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318935 | 0.93 | MMP9 (0.53) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7318343 | 0.92 | NAMPT (0.49) | MMP13MMP9MMP1NAMPTGAA | |
| SCHEMBL7316683 | 0.89 | NAMPT (0.52) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7322798 | 0.87 | NAMPT (0.49) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7316583 | 0.84 | NAMPT (0.53) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7324861 | 0.81 | NAMPT (0.52) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7319361 | 0.80 | MMP9 (0.56) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7316220 | 0.79 | NAMPT (0.53) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7317524 | 0.79 | NAMPT (0.53) | MMP13MMP9MMP1NAMPTADAM17 | |
| SCHEMBL7410709 | 0.76 | MMP9 (0.52) | MMP13MMP9MMP1NAMPTADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |