Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12171578 | 0.99 | NR1H4 (0.70) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL7323408 | 0.97 | RARB (0.75) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL8087307 | 0.96 | RARB (0.78) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL7314596 | 0.96 | RARB (0.78) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL7331833 | 0.95 | RARB (0.75) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL7342728 | 0.95 | RARB (0.75) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL7338309 | 0.95 | NR1H4 (0.68) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL12171858 | 0.93 | NR1H4 (0.70) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL8090549 | 0.89 | NPC1 (0.66) | RARBNR1H4NPC1RAB9ATSHR | |
| SCHEMBL7324596 | 0.89 | NPC1 (0.66) | RARBNR1H4NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |